Clinical trials for CLL & Richter's syndrome
41 currently recruiting clinical trials
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Phase 2
CLL & Richter's syndrome
#NCT04728893
#2023-504931-42-00
Required histologic types
Richter's syndrome
Required central nervous system lesions
None
Treated / Controled
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
5 recruiting sites
Merck Sharp & Dohme LLC
Phase 2
CLL & Richter's syndrome
#NCT05963074
#2023-504044-34-00
Required histologic types
CLL (Chronic Lymphocytic Leukemia)
Required central nervous system lesions
None
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
5 recruiting sites
Janssen
Phase 2
CLL & Richter's syndrome
#NCT06588478
#2024-515689-15-01
Required histologic types
CLL (Chronic Lymphocytic Leukemia)
Required number of previous lines of therapy
1
2
3 or more
Required previous treatments
Targeted therapy
Excluded previous treatments
Systemic Treatment-Naive
6 recruiting sites
Loxo Oncology
Phase 2
Lymphoma
CLL & Richter's syndrome
#NCT04728893
#2023-504931-42-00
Required histologic types
B cell lymphoma
CLL (Chronic Lymphocytic Leukemia)
Required histologic sub types
Lymphocytic lymphoma
Required central nervous system lesions
None
Treated / Controled
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
5 recruiting sites
Merck Sharp & Dohme LLC
Phase 2
CLL & Richter's syndrome
#NCT06588478
#2024-515689-15-01
Required histologic types
CLL (Chronic Lymphocytic Leukemia)
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
6 recruiting sites
Loxo Oncology
Phase 1 / Phase 2
Lymphoma
CLL & Richter's syndrome
Acute leukemia
Myelodysplastic Syndromes (MDS) and Myeloproliferative Neoplasms (MPN)
#NCT07220616
#2025-522595-87-00
Required central nervous system lesions
None
Treated / Controled
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
Allogeneic stem cell transplant
3 recruiting sites
Daiichi Sankyo
Phase 1 / Phase 2
Lymphoma
CLL & Richter's syndrome
#NCT05006716
Required histologic types
B cell lymphoma
CLL (Chronic Lymphocytic Leukemia)
Richter's syndrome
Required histologic sub types
Large B cell lymphoma
Mantel cell lymphoma
Follicular lymphoma
Marginal zone lymphoma
Waldenström lymphoma
Lymphocytic lymphoma
Required central nervous system lesions
None
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
9 recruiting sites
BeOne Medecines
Phase 1 / Phase 2
Lymphoma
CLL & Richter's syndrome
#NCT06564038
#2024-515034-33-00
Required histologic types
B cell lymphoma
CLL (Chronic Lymphocytic Leukemia)
Required histologic sub types
Lymphocytic lymphoma
Required number of previous lines of therapy
1
2
3 or more
Required previous treatments
Targeted therapy
Excluded previous treatments
Systemic Treatment-Naive
4 recruiting sites
AstraZeneca
Phase 1 / Phase 2
Lymphoma
CLL & Richter's syndrome
#NCT06564038
#2024-515034-33-00
Cohorte 1A et 1C
Required histologic types
B cell lymphoma
CLL (Chronic Lymphocytic Leukemia)
Required histologic sub types
Lymphocytic lymphoma
Required number of previous lines of therapy
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
4 recruiting sites
AstraZeneca
Phase 1 / Phase 2
Lymphoma
CLL & Richter's syndrome
Acute leukemia
#NCT04707300
#2019-004883-23
Required histologic types
CLL (Chronic Lymphocytic Leukemia)
Acute lymphoblastic leukemia (ALL)
Acute myeloid leukemia (AML)
4 recruiting sites
Assistance Publique - Hôpitaux de Paris