Clinical trials for CLL & Richter's syndrome

41 currently recruiting clinical trials
Phase 1 / Phase 2 Lymphoma CLL & Richter's syndrome #NCT06542250 #2024-511099-34-00
Required histologic types
B cell lymphoma CLL (Chronic Lymphocytic Leukemia)
Required histologic sub types
Large B cell lymphoma Mantel cell lymphoma Follicular lymphoma Lymphocytic lymphoma
Required central nervous system lesions
None
Required number of previous lines of therapy
2 3 or more
Excluded previous treatments
Systemic Treatment-Naive
2 recruiting sites
AstraZeneca
Phase 1 Breast cancer Lung cancer Pancreas cancer Lymphoma CLL & Richter's syndrome Ovarian / Fallopian tubes / Peritoneum cancer Sarcoma and GIST #NCT06823167 #2025-523160-20-00
Partie A
Required histologic types
NSCLC (Non-Small Cell Lung Cancer) Mesothelium B cell lymphoma Richter's syndrome Epithelial ovarian cancer Fallopian tube cancer Primary peritoneal cancer (PPC) Soft tissue sarcoma
Required histologic sub types
Non-squamous NSCLC Large B cell lymphoma Mantel cell lymphoma Follicular lymphoma Lymphocytic lymphoma
Required HER2 statuses
HER2 Negative
Required HR statuses
HR Negative
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy
1 2 3 or more
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
3 recruiting sites
Immunome, Inc.
Phase 1 Lymphoma CLL & Richter's syndrome #NCT05131022 #2023-510541-25-00
Cohortes non lymphome primitif du système nerveux central
Required histologic types
B cell lymphoma CLL (Chronic Lymphocytic Leukemia)
Required histologic sub types
Large B cell lymphoma Mantel cell lymphoma Follicular lymphoma Marginal zone lymphoma Waldenström lymphoma Lymphocytic lymphoma Indolent transformed lymphoma
Required central nervous system lesions
None
Required number of previous lines of therapy
2 3 or more
Excluded previous treatments
Systemic Treatment-Naive
7 recruiting sites
Nurix Therapeutics, Inc.
Phase 1 Lymphoma CLL & Richter's syndrome #NCT05544019 #2023-505204-34-00
Required histologic types
B cell lymphoma CLL (Chronic Lymphocytic Leukemia)
Required central nervous system lesions
None Treated / Controled
Required number of previous lines of therapy
1 2 3 or more
Excluded previous treatments
Systemic Treatment-Naive
1 recruiting site
Schrödinger, Inc.
Phase 1 Lymphoma CLL & Richter's syndrome #NCT05828459
Required number of previous lines of therapy
1 2 3 or more
Excluded previous treatments
Systemic Treatment-Naive
1 recruiting site
Onward Therapeutics