Clinical trials for Sarcoma and GIST

68 currently recruiting clinical trials

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Phase 2 Pancreas cancer Liver and bile duct cancer Stomach and esophageal cancer Sarcoma and GIST Small intestine and appendix cancer #NCT06333314 #2023-505298-34-00

[Pan-MSI-ACSE] DOSTARLIMAB pour le cancer localement avancé ou métastatique (non colorectal/non endométrial) avec tumeur dMMR/MSI

Stomach Oesogastric junction Soft tissue sarcoma Adenocarcinoma Ampullary carcinoma Locally Advanced Metastatic MSI/dMMR None Systemic Treatment-Naive CPS Negative (< 1) CPS Positive (1 <= X < 5)

Immunotherapy Radiotherapy

7 recruiting sites

UNICANCER

Phase 2 Endometrial cancer Sarcoma and GIST #NCT06524583 #2023-506350-21-00

[L-UteCIN] Intérêt de la chimiothérapie postopératoire chez les patientes atteintes d'un léiomyosarcome utérin localisé présentant un risque élevé de récidive suspecté d'après un test biologique réalisé sur la tumeur

Soft tissue sarcoma Other Stage I Localized None Systemic Treatment-Naive Surgery

2 recruiting sites

UNICANCER

Phase 2 Breast cancer Prostate cancer Colon cancer Rectal cancer Anal cancer Kidney cancer Pancreas cancer Liver and bile duct cancer Bladder / Urinary Tract / Urethral cancer Stomach and esophageal cancer Endometrial cancer Ovarian / Fallopian tubes / Peritoneum cancer Head and neck cancer Sarcoma and GIST Penile cancer and germ cell tumors Cervical / Vulvar / Vaginal cancer #NCT06760819 #2024-517419-62-00

[panSOHO] Etude sur l'efficacité du BAY2927088 et sur son innocuité chez les participants atteints d'une tumeur solide présentant des mutations activatices d'HER2

Stomach Oesogastric junction Esophagus Adenocarcinoma Intrahepatic cholangiocarcinoma Extrahepatic cholangiocarcinoma Ampullary carcinoma Gastrointestinal stromal tumor Squamous cell carcinoma Other HER2 Positive Locally Advanced Metastatic Metastatic Castration-resistant HER2 1

Systemic Treatment-Naive

6 recruiting sites

Bayer

Phase 2 Stomach and esophageal cancer Sarcoma and GIST #NCT05152472 #2022-503068-34-00

[ATEZOGIST] Étude prospective, randomisée, multicentrique et comparative de l'efficacité de la reprise de l'imatinib combinée à l'atézolizumab par rapport à la reprise de l'imatinib seul chez les patients atteints de tumeurs stromales gastro-intestinales (GIST) avancées non résécables après échec des traitements standards

GIST Gastrointestinal stromal tumor Locally Advanced Metastatic 3 or more Targeted therapy

Systemic Treatment-Naive Immunotherapy

11 recruiting sites

Centre Léon Bérard

Phase 2 Stomach and esophageal cancer Sarcoma and GIST #NCT05009927 #2024-512631-77-00

[GIST-Ten] Efficacité du traitement par imatinib après 10 ans de traitement chez les patients atteints de tumeurs stromales gastro-intestinales (GIST)

GIST Gastrointestinal stromal tumor Locally Advanced Metastatic KIT None Chemotherapy

Systemic Treatment-Naive

6 recruiting sites

Centre Léon Bérard

Phase 2 Sarcoma and GIST #NCT03548428 #2024-511313-38-00

[Stéréosarc] Irradiation stéréotaxique corporelle des oligométastases dans le sarcome

Soft tissue sarcoma Metastatic None 1

Immunotherapy

5 recruiting sites

Centre Antoine Lacassagne

Phase 2 Sarcoma and GIST #NCT06022159

[HYPOSARC] Une étude visant à évaluer la radiothérapie hypofractionnée préopératoire chez les patients âgés (≥ 70 ans) ou « fragiles » (≥ 65 ans) atteints d'un sarcome des tissus mous des membres ou du tronc.

Soft tissue sarcoma Localized None Systemic Treatment-Naive

Chemotherapy Radiotherapy

11 recruiting sites

Institut Claudius Regaud

Phase 2 Sarcoma and GIST #NCT04698785

[REGOMAIN] Efficacité du régorafénib associé aux meilleurs soins de soutien en tant que traitement d'entretien chez les patients atteints de sarcomes osseux de haut grade

Bone sarcoma Locally Advanced None 1 Systemic Treatment-Naive Chemotherapy

Targeted therapy

8 recruiting sites

Centre Léon Bérard

Phase 2 Sarcoma and GIST #NCT05182164 #2023-509496-16-00

Association de pembrolizumab et de cabozantinib chez les patients atteints de sarcomes avancés

Bone sarcoma Soft tissue sarcoma Osteosarcoma Ewing tumor Locally Advanced Metastatic 1 2 3 or more

Systemic Treatment-Naive Immunotherapy

6 recruiting sites

Institut Bergonié

Phase 2 Sarcoma and GIST #NCT04874311 #2020-005703-39

[TRUST] Bintrafusp Alfa et chlorhydrate de doxorubicine dans le traitement des patients atteints de sarcome avancé

Soft tissue sarcoma Locally Advanced Metastatic None Systemic Treatment-Naive

Immunotherapy Immunotherapy Chemotherapy

3 recruiting sites

Institut Bergonié