Clinical trials for Sarcoma and GIST

71 currently recruiting clinical trials
Phase 1 / Phase 2 Stomach and esophageal cancer Sarcoma and GIST #NCT05957367 #2024-516476-15-00
Module B Partie 2
GIST Gastrointestinal stromal tumor Locally Advanced Metastatic KIT 1 Targeted therapy
Systemic Treatment-Naive
2 recruiting sites
Deciphera Pharmaceuticals, LLC
Phase 1 / Phase 2 Stomach and esophageal cancer Sarcoma and GIST #NCT05957367 #2024-516476-15-00
Module B Partie 1
GIST Gastrointestinal stromal tumor Locally Advanced Metastatic KIT PDGFRA 1 2 3 or more
Systemic Treatment-Naive
2 recruiting sites
Deciphera Pharmaceuticals, LLC
Phase 1 / Phase 2 Breast cancer Prostate cancer Colon cancer Rectal cancer Anal cancer Kidney cancer Pancreas cancer Liver and bile duct cancer Bladder / Urinary Tract / Urethral cancer Stomach and esophageal cancer Endometrial cancer Ovarian / Fallopian tubes / Peritoneum cancer Head and neck cancer Sarcoma and GIST Thymus cancer Penile cancer and germ cell tumors #NCT05118789
Locally Advanced Metastatic ROS-1 1
4 recruiting sites
Nuvalent Inc.
Phase 1 / Phase 2 Sarcoma and GIST #NCT02275286 #2024-518199-30-00
Cohorte D
Soft tissue sarcoma Localized None 1 Systemic Treatment-Naive Chemotherapy Retroperitoneum Grade 2
Surgery Radiotherapy
2 recruiting sites
Grupo Espanol de Investigacion en Sarcomas
Phase 1 / Phase 2 Sarcoma and GIST #NCT02275286 #2024-518199-30-00
Cohorte C
Soft tissue sarcoma Localized None Systemic Treatment-Naive Retroperitoneum Grade 2 Grade 3
Surgery Chemotherapy Radiotherapy
2 recruiting sites
Grupo Espanol de Investigacion en Sarcomas
Phase 1 / Phase 2 Sarcoma and GIST #NCT02275286 #2024-518199-30-00
Cohorte D
Soft tissue sarcoma Localized None 1 Systemic Treatment-Naive Chemotherapy Retroperitoneum
2 recruiting sites
Grupo Espanol de Investigacion en Sarcomas
Phase 1 / Phase 2 Sarcoma and GIST #NCT02275286 #2024-518199-30-00
Cohorte C
Soft tissue sarcoma Localized Systemic Treatment-Naive Retroperitoneum
Surgery Chemotherapy Radiotherapy
2 recruiting sites
Grupo Espanol de Investigacion en Sarcomas
Phase 1 / Phase 2 Sarcoma and GIST #NCT06797999 #2024-516900-41-00
Soft tissue sarcoma Locally Advanced Metastatic 1 2 Chemotherapy
Systemic Treatment-Naive
1 recruiting site
Adcendo ApS
Phase 1 Breast cancer Prostate cancer Colon cancer Rectal cancer Anal cancer Pancreas cancer Liver and bile duct cancer Bladder / Urinary Tract / Urethral cancer Stomach and esophageal cancer Endometrial cancer Ovarian / Fallopian tubes / Peritoneum cancer Head and neck cancer Sarcoma and GIST Thymus cancer Penile cancer and germ cell tumors Cervical / Vulvar / Vaginal cancer #NCT04777994
Dose d'expansion cohorte combinaison avec inhibiteur PD-1 tumeurs MSI-H
Locally Advanced Metastatic MSI/dMMR 1 2 3 or more Immunotherapy
Systemic Treatment-Naive
4 recruiting sites
Calico Life Sciences LLC
Phase 1 Breast cancer Lung cancer Prostate cancer Colon cancer Rectal cancer Anal cancer Kidney cancer Pancreas cancer Liver and bile duct cancer Bladder / Urinary Tract / Urethral cancer Stomach and esophageal cancer Endometrial cancer Ovarian / Fallopian tubes / Peritoneum cancer Head and neck cancer Sarcoma and GIST Thymus cancer Penile cancer and germ cell tumors Cervical / Vulvar / Vaginal cancer Small intestine and appendix cancer Thyroid and adrenal gland cancer #NCT06551142 #2024-513663-10
Phase 1a
Locally Advanced Metastatic Metastatic Castration-resistant 1 2 3 or more
Systemic Treatment-Naive
3 recruiting sites
GlaxoSmithKline