Cancer clinical trials in the region Pays de la Loire
433 currently recruiting clinical trials
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Phase 1 / Phase 2
Lung cancer
#NCT04585750
#2023-504251-27-00
Phase 2 cohorte de patients atteints de cancer du poumon
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
TP53
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Excluded genetic anomalies
KRAS G12C
KRAS non G12C
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
9 recruiting sites
PMV Pharmaceuticals, Inc
Phase 1 / Phase 2
Breast cancer
#NCT04585750
#2023-504251-27-00
Phase 2 cohorte de cancer du sein
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
TP53
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Excluded genetic anomalies
KRAS G12C
KRAS non G12C
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
9 recruiting sites
PMV Pharmaceuticals, Inc
Phase 1 / Phase 2
Endometrial cancer
#NCT04585750
#2023-504251-27-00
Phase 2 cohorte de patients atteints d'un cancer de l'endomètre
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
TP53
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Excluded genetic anomalies
KRAS G12C
KRAS non G12C
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
9 recruiting sites
PMV Pharmaceuticals, Inc
Phase 1 / Phase 2
Lung cancer
#NCT06043817
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
EGFR
HER2
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
3 recruiting sites
Laboratoires Pierre Fabre
Phase 1 / Phase 2
Prostate cancer
#NCT07226986
#2025-521859-23-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic Castration-resistant
Required PSMA PET Scan statuses
PSMA PET Positive
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Hormone therapy
4 recruiting sites
Novartis
Phase 1 / Phase 2
Acute leukemia
#NCT04811560
Phase 2
Required histologic types
Acute myeloid leukemia (AML)
Required central nervous system lesions
None
Treated / Controled
Required genetic anomalies
KMT2A
NPM1
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
11 recruiting sites
Janssen
Phase 1 / Phase 2
Acute leukemia
#NCT04811560
Phase 1
Required central nervous system lesions
None
Treated / Controled
Required genetic anomalies
Other mutation
KMT2A
NPM1
NUP214
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
11 recruiting sites
Janssen
Phase 1 / Phase 2
Acute leukemia
#NCT06356922
Required histologic types
Acute lymphoblastic leukemia (ALL)
Acute myeloid leukemia (AML)
Required central nervous system lesions
None
Required renal function statuses
> 60 ml/min
50-60 ml/min
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
4 recruiting sites
Hôpital universitaire de Nantes
Phase 1 / Phase 2
Breast cancer
Prostate cancer
Colon cancer
Rectal cancer
Anal cancer
Kidney cancer
Pancreas cancer
Liver and bile duct cancer
Bladder / Urinary Tract / Urethral cancer
Stomach and esophageal cancer
Endometrial cancer
Ovarian / Fallopian tubes / Peritoneum cancer
Head and neck cancer
Sarcoma and GIST
Thymus cancer
Penile cancer and germ cell tumors
#NCT05118789
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
ROS-1
Required number of previous lines of therapy for current stage of disease
1
4 recruiting sites
Nuvalent Inc.
Phase 1 / Phase 2
Acute leukemia
#NCT04988555
[Horizen-1 Étude de phase 1/2 de l'Enzomenib (DSP-5336) chez les patients atteints de leucémie aiguë
Phase 1, Bras L, M et N
Required histologic types
Acute myeloid leukemia (AML)
Required central nervous system lesions
None
Treated / Controled
Required renal function statuses
> 60 ml/min
50-60 ml/min
Required genetic anomalies
KMT2A
NPM1
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
8 recruiting sites
Sumitomo Pharma America, Inc.