Cancer clinical trials in the region Pays de la Loire
433 currently recruiting clinical trials
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Phase 1 / Phase 2
Acute leukemia
#NCT04988555
#2022-502741-10-00
Phase 2, Bras G, H et K
Required histologic types
Acute myeloid leukemia (AML)
Required central nervous system lesions
None
Treated / Controled
Required renal function statuses
> 60 ml/min
50-60 ml/min
Required genetic anomalies
MLL fusions
NPM1
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
8 recruiting sites
Sumitomo Pharma America, Inc.
Phase 1 / Phase 2
Acute leukemia
#NCT04988555
Phase 2, bras J
Required genetic anomalies
MLL fusions
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
8 recruiting sites
Sumitomo Pharma America, Inc.
Phase 1 / Phase 2
Acute leukemia
#NCT04988555
#2022-502741-10-00
Phase 2 - Bras I
Required histologic types
Acute lymphoblastic leukemia (ALL)
Required central nervous system lesions
None
Required renal function statuses
> 60 ml/min
50-60 ml/min
Required genetic anomalies
KMT2A
Required number of previous lines of therapy
1
2
3 or more
8 recruiting sites
Sumitomo Pharma America, Inc.
Phase 1 / Phase 2
Lung cancer
Bladder / Urinary Tract / Urethral cancer
Stomach and esophageal cancer
Head and neck cancer
#NCT06923761
#2023-504845-30-00
Module 2 Cohorte 3 Tumeurs solides avec un TMB médian modéré à élevé
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Stomach
Oesogastric junction
Esophagus
Invasive bladder cancer
Oral cavity
Nasopharynx
Oropharynx
Hypopharynx
Larynx
Nasal cavities and sinuses
Required histologic sub types
Adenocarcinoma
Squamous cell carcinoma
Urothelial carcinoma
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
1
2
Required previous treatments at advanced or metastatic stage
Immunotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
7 recruiting sites
Grey Wolf Therapeutics
Phase 1 / Phase 2
Lung cancer
#NCT06128551
Phase 1b expansion de dose et phase 2 cohortes CBNPC non naïf d'inhibiteurs de KRAS G12C
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
KRAS G12C
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Required previous treatments at advanced or metastatic stage
Immunotherapy
Chemotherapy
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
7 recruiting sites
Revolution Medicines, Inc.
Phase 1 / Phase 2
Lung cancer
#NCT06162221
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
Other KRAS
HRAS
KRAS G12C
KRAS non G12C
KRAS G12D
NRAS
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Excluded previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
13 recruiting sites
Revolution Medicines, Inc.
Phase 1 / Phase 2
Acute leukemia
#NCT05768035
Required histologic types
Acute lymphoblastic leukemia (ALL)
Acute myeloid leukemia (AML)
Required number of previous lines of therapy
1
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
Allogeneic stem cell transplant
4 recruiting sites
Smart Immune SAS
Phase 1 / Phase 2
Acute leukemia
#NCT04150497
Required histologic types
Acute lymphoblastic leukemia (ALL)
Required histologic sub types
B-cell (B-ALL)
Required number of previous lines of therapy
2
3 or more
Excluded previous treatments
Systemic Treatment-Naive
4 recruiting sites
Cellectis SA
Phase 1 / Phase 2
Prostate cancer
#NCT06907043
#2024-520395-99-00
Cohorte cancer de la prostate résistant à la castration
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic Castration-resistant
Required genetic anomalies
ATM
BRCA 1/2
CHEK 1/2
Other mutation
PALB2
Required number of previous lines of therapy for current stage of disease
1
2
Required previous treatments at advanced or metastatic stage
Chemotherapy
Hormone therapy
2 recruiting sites
Eikon Therapeutics
Phase 1 / Phase 2
Ovarian / Fallopian tubes / Peritoneum cancer
#NCT06907043
#2024-520395-99-00
Cohorte cancer de l'ovaire
Required histologic types
Epithelial ovarian cancer
Fallopian tube cancer
Primary peritoneal cancer (PPC)
Required histologic sub types
Serous high grade carcinoma (HGSOC)
Endometrioid carcinoma
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
BRCA 1/2
ATM
Other mutation
CHEK 1/2
PALB2
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Required previous treatments at advanced or metastatic stage
Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
2 recruiting sites
Eikon Therapeutics