Hôpital Européen Georges Pompidou - AP-HP

56 currently recruiting clinical trials
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Phase 2 Colon cancer Rectal cancer #NCT06948448 #2024-519590-19-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Locally Advanced Metastatic
Required genetic anomalies
MSS/pMMR
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
Hôpital Européen Georges Pompidou - AP-HP (Paris)
Ono Pharmaceutical Co. Ltd.
Phase 2 Colon cancer Rectal cancer #NCT04262687
Required disease stage
Metastatic
Required genetic anomalies
MSS/pMMR
Required number of previous lines of therapy for current stage of disease
None 1
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive Surgery Chemotherapy
Excluded genetic anomalies
MSI/dMMR
Excluded previous treatments at localized stage
Immunotherapy
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
Hôpital Européen Georges Pompidou - AP-HP (Paris)
Fédération Francophone de Cancérologie Digestive
Phase 2 Colon cancer Rectal cancer #NCT06820463 #2024-512981-33-00
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Européen Georges Pompidou - AP-HP (Paris)
Abbvie
Phase 2 Colon cancer Rectal cancer Anal cancer Pancreas cancer Liver and bile duct cancer Stomach and esophageal cancer #NCT06475352
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Européen Georges Pompidou - AP-HP (Paris)
UNICANCER
Phase 2 Colon cancer Rectal cancer #NCT05706779
Required histologic sub types
Adenocarcinoma
Required disease stage
Localized
Required genetic anomalies
BRAF
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Excluded genetic anomalies
KRAS G12C KRAS non G12C NRAS
Excluded previous treatments at localized stage
Targeted therapy
Hôpital Européen Georges Pompidou - AP-HP (Paris)
Fédération Francophone de Cancérologie Digestive
Phase 2 Bladder / Urinary Tract / Urethral cancer #NCT04617756
Required histologic types
Upper excretory tract cancer
Required histologic sub types
Urothelial carcinoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Surgery
Hôpital Européen Georges Pompidou - AP-HP (Paris)
Centre Hospitalier Universitaire de Nîmes
Phase 1 / Phase 2 Stomach and esophageal cancer Sarcoma and GIST #NCT05957367 #2024-516476-15-00
Module B Partie 2
Required histologic types
GIST
Required histologic sub types
Gastrointestinal stromal tumor
Required disease stage
Locally Advanced Metastatic
Required genetic anomalies
KIT
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Européen Georges Pompidou - AP-HP (Paris)
Deciphera Pharmaceuticals, LLC
Phase 1 / Phase 2 Stomach and esophageal cancer Sarcoma and GIST #NCT05957367 #2024-516476-15-00
Module B Partie 1
Required histologic types
GIST
Required histologic sub types
Gastrointestinal stromal tumor
Required disease stage
Locally Advanced Metastatic
Required genetic anomalies
KIT PDGFRA
Required number of previous lines of therapy for current stage of disease
1 2 3 or more
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Européen Georges Pompidou - AP-HP (Paris)
Deciphera Pharmaceuticals, LLC
Phase 1 / Phase 2 Prostate cancer #NCT07206056 #2025-521880-10-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic Castration-resistant
Required number of previous lines of therapy for current stage of disease
1 2 3 or more
Required previous treatments at advanced or metastatic stage
Hormone therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Européen Georges Pompidou - AP-HP (Paris)
Novartis
Phase 1 / Phase 2 Pancreas cancer #NCT06885034 #2025-520672-26-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Européen Georges Pompidou - AP-HP (Paris)
GlaxoSmithKline