Hôpital Pitié Salpêtrière - AP-HP

98 currently recruiting clinical trials

Phase 3 Brain tumors / Central nervous system tumors #NCT06556563 #2024-513550-30-00
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
None
Required previous treatments
Surgery Chemotherapy Radiotherapy Radiochemotherapy
Excluded previous treatments
Systemic Treatment-Naive Immunotherapy
Hôpital Pitié Salpêtrière - AP-HP (Paris)
NovoCure GmbH
Phase 3 Brain tumors / Central nervous system tumors #NCT05902169 #2023-505829-14-00
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
1
Required previous treatments
Surgery Immunotherapy Chemotherapy Radiotherapy
Excluded genetic anomalies
BRAF IDH1/2 NTRK-1/2/3
Excluded previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
CarThera
Phase 3 Brain tumors / Central nervous system tumors #NCT05904119
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
1
Required previous treatments
Surgery Radiochemotherapy
Excluded genetic anomalies
IDH1/2
Excluded previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 3 Brain tumors / Central nervous system tumors #NCT05476939 #2014-001929-32
Required histologic types
Gliomas
Required histologic sub types
Diffuse midline glioma grade IV
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded previous treatments
Chemotherapy Radiotherapy
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Gustave Roussy, Campus du cancer, Grand Paris
Phase 3 Brain tumors / Central nervous system tumors #NCT05476939 #2014-001929-32
Phase inclusion - gliomes diffus de la ligne médiane non-DIPG
Required histologic types
Gliomas
Required histologic sub types
Diffuse midline glioma grade IV
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded previous treatments
Chemotherapy Radiotherapy
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Gustave Roussy, Campus du cancer, Grand Paris
Phase 3 Brain tumors / Central nervous system tumors #NCT04702581
Required histologic types
Gliomas
Required histologic sub types
Oligodendroglioma grade II
Required genetic anomalies
IDH1/2
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive Surgery
Excluded previous treatments
Chemotherapy Radiotherapy
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Hospices Civils de Lyon
Phase 3 Lymphoma CLL & Richter's syndrome #NCT05254743 #2023-507699-38-00
Required histologic types
B cell lymphoma CLL (Chronic Lymphocytic Leukemia)
Required histologic sub types
Lymphocytic lymphoma
Required central nervous system lesions
None
Required renal function statuses
> 60 ml/min 50-60 ml/min 30-50 ml/min
Required genetic anomalies
Other mutation
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Loxo Oncology
Phase 3 Multiple myeloma #NCT06918002 #2024-516418-39-00
Required histologic types
Symptomatic multiple myeloma
Required histologic sub types
Monoclonal component measurable
Required central nervous system lesions
None
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Intergroupe Francophone du Myélome
Phase 3 Thyroid and adrenal gland cancer #NCT04290663 #2024-514603-34-00
Required histologic types
Thyroid cancer
Required histologic sub types
Differentiated carcinoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive Surgery
Excluded previous treatments at localized stage
Radioactive iodine
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Centre François Baclesse
Phase 3 Head and neck cancer #NCT06496178 #2023-510322-32-00
Required histologic types
Oral cavity Oropharynx Hypopharynx Larynx
Required histologic sub types
Squamous cell carcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Immunotherapy Chemotherapy
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Merus