Hôpital Pitié Salpêtrière - AP-HP

98 currently recruiting clinical trials
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Phase 2 / Phase 3 Lymphoma Acute leukemia #NCT06860269 #2024-511437-35-00
GRAALL-2024/T - LAL-T/LL
Required histologic types
T cell lymphoma Acute lymphoblastic leukemia (ALL)
Required histologic sub types
T-cell (T-ALL)
Required disease stage
Disseminated (stage III and IV)
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded previous treatments
Chemotherapy Targeted therapy Monoclonal antibodies
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Assistance Publique - Hôpitaux de Paris
Phase 2 / Phase 3 Colon cancer Rectal cancer #NCT05462613 #2024-516709-22-00
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Surgery Chemotherapy Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
CHU de Besançon
Phase 2 Lymphoma #NCT05139017 #2022-502646-27-00
Required histologic types
B cell lymphoma
Required histologic sub types
Large B cell lymphoma
Required central nervous system lesions
None Treated / Controled
Required number of previous lines of therapy
1 2 3 or more
Required previous treatments
Car-T Autologous stem cell transplant
Excluded previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Merck Sharp & Dohme LLC
Phase 2 Lymphoma #NCT04984837 #2024-513252-15-00
Required histologic types
T cell lymphoma
Required histologic sub types
Peripheral T cell lymphoma
Required central nervous system lesions
None
Required renal function statuses
> 60 ml/min 50-60 ml/min 30-50 ml/min
Required number of previous lines of therapy
1 2
Required previous treatments
Chemotherapy
Excluded previous treatments
Systemic Treatment-Naive Allogeneic stem cell transplant
Hôpital Pitié Salpêtrière - AP-HP (Paris)
The Lymphoma Academic Research Organisation (LYSARC)
Phase 2 Lymphoma Brain tumors / Central nervous system tumors #NCT03328078 #2024-513312-95-00
Required histologic types
B cell lymphoma Other primary CNS tumor
Required histologic sub types
Primary cerebral lymphoma Primary CNS lymphoma
Required number of previous lines of therapy
1 2 3 or more
Excluded previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Curis, Inc.
Phase 2 Lymphoma Brain tumors / Central nervous system tumors #NCT07015242 #2025-521144-38-00
Required histologic types
B cell lymphoma Other primary CNS tumor
Required histologic sub types
Primary cerebral lymphoma Primary CNS lymphoma
Required central nervous system lesions
Actives
Required number of previous lines of therapy
None
Excluded previous treatments
Car-T Allogeneic stem cell transplant
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 2 Brain tumors / Central nervous system tumors #NCT03970447 #2024-511452-40-00
GBM récurrent
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
1 2
Required previous treatments
Chemotherapy Radiotherapy
Excluded genetic anomalies
IDH1/2
Excluded previous treatments
Systemic Treatment-Naive Bevacizumab
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Global Coalition for Adaptive Research
Phase 2 Brain tumors / Central nervous system tumors #NCT03970447 #2024-511452-40-00
GBM 1L
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded genetic anomalies
IDH1/2
Excluded previous treatments
Immunotherapy Chemotherapy Radiotherapy Radiochemotherapy
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Global Coalition for Adaptive Research
Phase 2 Brain tumors / Central nervous system tumors #NCT04945148 #2024-511026-31-01
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive Surgery
Excluded genetic anomalies
IDH1/2
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Hopital Foch
Phase 2 Brain tumors / Central nervous system tumors #NCT05503797 #2024-513578-23-00
Sous-protocole B
Required genetic anomalies
BRAF
Required number of previous lines of therapy
1 2 3 or more
Required previous treatments
Chemotherapy Radiotherapy Radiochemotherapy
Excluded genetic anomalies
HRAS Other KRAS KRAS G12C KRAS G12D KRAS non G12C NRAS RAS
Excluded previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Fore Biotherapeutics