Hôpital Pitié Salpêtrière - AP-HP

98 currently recruiting clinical trials
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Phase 2 CLL & Richter's syndrome #NCT05963074 #2023-504044-34-00
Required histologic types
CLL (Chronic Lymphocytic Leukemia)
Required central nervous system lesions
None
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Janssen
Phase 2 Lymphoma #NCT05963074 #2023-504044-34-00
Required histologic types
B cell lymphoma
Required histologic sub types
Lymphocytic lymphoma
Required central nervous system lesions
None
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Janssen
Phase 2 Liver and bile duct cancer #NCT05528952
Required histologic sub types
Hepatocellular carcinoma
Required disease stage
Locally Advanced Metastatic
Required liver status
Unhealthy
Required Child-Pugh scores
A
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
Hôpital Pitié Salpêtrière - AP-HP (Paris)
CHU de Besançon
Phase 2 Bladder / Urinary Tract / Urethral cancer #NCT04617756
Required histologic types
Upper excretory tract cancer
Required histologic sub types
Urothelial carcinoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Surgery
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Centre Hospitalier Universitaire de Nîmes
Phase 1 / Phase 2 Breast cancer Lung cancer Prostate cancer Colon cancer Rectal cancer Anal cancer Kidney cancer Pancreas cancer Liver and bile duct cancer Bladder / Urinary Tract / Urethral cancer Stomach and esophageal cancer Endometrial cancer Ovarian / Fallopian tubes / Peritoneum cancer Head and neck cancer #NCT04657068 #2024-511534-12-00
Dose d'expansion Partie B4
Required disease stage
Locally Advanced Metastatic Metastatic Castration-resistant
Required genetic anomalies
ATM
Required number of previous lines of therapy for current stage of disease
1 2 3 or more
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Artios Pharma Ltd
Phase 1 / Phase 2 Stomach and esophageal cancer #NCT06780111 #2024-514273-22-00
Required histologic types
Esophagus
Required histologic sub types
Squamous cell carcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Merck Sharp & Dohme LLC
Phase 1 / Phase 2 Brain tumors / Central nervous system tumors #NCT06622434 #2024-514567-26-00
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded previous treatments
Immunotherapy Chemotherapy Radiotherapy Bevacizumab
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Assistance Publique - Hôpitaux de Paris
Phase 1 / Phase 2 Breast cancer #NCT05386108 #2024-512878-98-00
Phase 2
Required HER2 statuses
HER2 Negative
Required HR statuses
HR Positive
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
1 2 3 or more
Required previous treatments at advanced or metastatic stage
Chemotherapy Targeted therapy Hormone therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Stemline Therapeutics, Inc.
Phase 1 / Phase 2 Stomach and esophageal cancer #NCT06445972 #2023-509306-29-00
Required histologic types
Stomach Oesogastric junction Esophagus
Required histologic sub types
Adenocarcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Chemotherapy
Excluded genetic anomalies
HER2
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Merck Sharp & Dohme LLC
Phase 1 / Phase 2 Stomach and esophageal cancer #NCT06469944 #2023-509307-33-00
Required histologic types
Stomach Oesogastric junction Esophagus
Required histologic sub types
Adenocarcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded genetic anomalies
HER2
Excluded previous treatments at advanced or metastatic stage
Immunotherapy Antibody Drug Conjugates (ADC)
Hôpital Pitié Salpêtrière - AP-HP (Paris)
Merck Sharp & Dohme LLC