Cancer clinical trials in the region Grand Est
285 currently recruiting clinical trials
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Phase 2
Lymphoma
#NCT04844866
Required histologic types
B cell lymphoma
Required histologic sub types
Large B cell lymphoma
Primary mediastinal lymphoma
Follicular lymphoma
Indolent transformed lymphoma
Required central nervous system lesions
None
Required number of previous lines of therapy
1
Required previous treatments
Chemotherapy
Targeted therapy
Excluded previous treatments
Systemic Treatment-Naive
Car-T
5 recruiting sites
Miltenyi Biomedicine GmbH
Phase 2
Stomach and esophageal cancer
Sarcoma and GIST
#NCT05152472
#2022-503068-34-00
Required histologic types
GIST
Required histologic sub types
Gastrointestinal stromal tumor
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
3 or more
Required previous treatments at advanced or metastatic stage
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Immunotherapy
11 recruiting sites
Centre Léon Bérard
Phase 2
Liver and bile duct cancer
#NCT06254248
#2024-514400-14-00
Required histologic sub types
Hepatocellular carcinoma
Required disease stage
Locally Advanced
Metastatic
Required liver status
Unhealthy
Required Child-Pugh scores
A
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Transplant
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
10 recruiting sites
Assistance Publique - Hôpitaux de Paris
Phase 2
Ovarian / Fallopian tubes / Peritoneum cancer
#NCT05128825
Partie partie 2b et 2c (Cyclin E1 positive)
Required histologic types
Epithelial ovarian cancer
Fallopian tube cancer
Primary peritoneal cancer (PPC)
Required histologic sub types
Serous high grade carcinoma (HGSOC)
Required genetic anomalies
Other mutation
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Required platino resistance
Recurrence within 6 months after platinum-based tr...
Required previous treatments at localized stage
Chemotherapy
Required previous treatments at advanced or metastatic stage
Chemotherapy
Excluded previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
12 recruiting sites
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 2
Stomach and esophageal cancer
Sarcoma and GIST
#NCT05009927
#2024-512631-77-00
Required histologic types
GIST
Required histologic sub types
Gastrointestinal stromal tumor
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
KIT
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
6 recruiting sites
Centre Léon Bérard
Phase 2
Sarcoma and GIST
#NCT03548428
#2024-511313-38-00
Required histologic types
Soft tissue sarcoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
1
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
5 recruiting sites
Centre Antoine Lacassagne
Phase 2
Breast cancer
#NCT06680596
#2024-515349-41-00
Required HER2 statuses
HER2 Low
Required HR statuses
HR Positive
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Excluded previous treatments at advanced or metastatic stage
Antibody Drug Conjugates (ADC)
Hormone therapy
34 recruiting sites
UNICANCER
Phase 2
Colon cancer
Rectal cancer
Stomach and esophageal cancer
#NCT06245356
#2023-508724-35-00
Required histologic types
Stomach
Oesogastric junction
Esophagus
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
4 recruiting sites
UNICANCER
Phase 2
Lung cancer
#NCT06620835
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
ALK
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Targeted therapy
4 recruiting sites
Groupe Français de Pneumo-Cancérologie
Phase 2
Sarcoma and GIST
#NCT04698785
Required histologic types
Bone sarcoma
Required disease stage
Locally Advanced
Required number of previous lines of therapy for current stage of disease
None
1
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Targeted therapy
8 recruiting sites
Centre Léon Bérard