Cancer clinical trials in the region Grand Est
294 currently recruiting clinical trials
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Phase 2
Ovarian / Fallopian tubes / Peritoneum cancer
#NCT07059845
#2025-521606-18-00
Required histologic types
Epithelial ovarian cancer
Fallopian tube cancer
Primary peritoneal cancer (PPC)
Required histologic sub types
Serous high grade carcinoma (HGSOC)
Required FIGO stages
Stage III
Stage IV
Required number of previous lines of therapy for current stage of disease
1
2
Required platino resistance
Recurrence 6 months or more after platinum treatme...
Required previous treatments at advanced or metastatic stage
Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Antibody Drug Conjugates (ADC)
13 recruiting sites
Abbvie
Phase 2
Thyroid and adrenal gland cancer
#NCT03732495
Required histologic types
Thyroid cancer
Required histologic sub types
Differentiated carcinoma
Poorly differentiated carcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Radioactive iodine
Required radioactive iodine status
Resistant to radioactive iodine
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Targeted therapy
14 recruiting sites
Centre Léon Bérard
Phase 2
Lung cancer
#NCT04613596
#2023-508922-83-00
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
KRAS G12C
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
17 recruiting sites
Mirati Thérapeutique Inc.
Phase 2
Bladder / Urinary Tract / Urethral cancer
#NCT06172478
#2023-507641-29-00
Carcinome urothélial
Required histologic types
Invasive bladder cancer
Upper excretory tract cancer
Urethral cancer
Required histologic sub types
Urothelial carcinoma
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Required previous treatments at advanced or metastatic stage
Immunotherapy
Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
9 recruiting sites
Daiichi Sankyo
Phase 2
Colon cancer
Rectal cancer
Anal cancer
#NCT04954820
Required histologic sub types
Neuroendocrine tumor
Required number of previous lines of therapy for current stage of disease
1
Required SSTR metabolic imaging statuses
SSTR Positive
Excluded previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
26 recruiting sites
Institut du Cancer de Montpellier - Val d'Aurelle
Phase 2
Pancreas cancer
Stomach and esophageal cancer
#NCT04325425
#2024-515300-39-00
Required histologic types
Stomach
Required histologic sub types
Neuroendocrine carcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Chemotherapy
Targeted therapy
17 recruiting sites
CHU Dijon
Phase 2
Breast cancer
#NCT05973864
#2023-505291-30-01
Required HER2 statuses
HER2 Negative
Required HR statuses
HR Negative
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Surgery
Immunotherapy
Chemotherapy
20 recruiting sites
UNICANCER
Phase 2
Lymphoma
#NCT04844866
Required histologic types
B cell lymphoma
Required histologic sub types
Large B cell lymphoma
Primary mediastinal lymphoma
Follicular lymphoma
Indolent transformed lymphoma
Required central nervous system lesions
None
Required number of previous lines of therapy
1
Required previous treatments
Chemotherapy
Targeted therapy
Excluded previous treatments
Systemic Treatment-Naive
Car-T
5 recruiting sites
Miltenyi Biomedicine GmbH
Phase 2
Stomach and esophageal cancer
Sarcoma and GIST
#NCT05152472
#2022-503068-34-00
Required histologic types
GIST
Required histologic sub types
Gastrointestinal stromal tumor
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
3 or more
Required previous treatments at advanced or metastatic stage
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Immunotherapy
12 recruiting sites
Centre Léon Bérard
Phase 2
Liver and bile duct cancer
#NCT06254248
#2024-514400-14-00
Required histologic sub types
Hepatocellular carcinoma
Required disease stage
Locally Advanced
Metastatic
Required liver status
Unhealthy
Required Child-Pugh scores
A
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Transplant
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
10 recruiting sites
Assistance Publique - Hôpitaux de Paris