Cancer clinical trials in the region Centre-Val de Loire

48 currently recruiting clinical trials

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Early Access Lung cancer

Accès précoce pré-AMM– RYBREVANT 350 mg

NSCLC (Non-Small Cell Lung Cancer) Locally Advanced Metastatic EGFR Targeted therapy

Systemic Treatment-Naive

6 main criterias to confirm

Janssen

Early Access Lung cancer

Accès précoce pré-AMM– RYBREVANT 350 mg

NSCLC (Non-Small Cell Lung Cancer) Locally Advanced Metastatic EGFR None Systemic Treatment-Naive

7 main criterias to confirm

Janssen

Early Access Lung cancer

Accès précoce pré-AMM– TAGRISSO (osimertinib)

NSCLC (Non-Small Cell Lung Cancer) Non-squamous NSCLC Locally Advanced EGFR None Chemotherapy Radiotherapy

8 main criterias to confirm

AstraZeneca

Early Access Lung cancer

Accès précoce post-AMM– ALECENSA (alectinib)

NSCLC (Non-Small Cell Lung Cancer) Localized ALK None Systemic Treatment-Naive Surgery

8 main criterias to confirm

Hoffmann-La Roche

Early Access Lung cancer

Accès précoce – OPDIVO (nivolumab)

NSCLC (Non-Small Cell Lung Cancer) Localized PDL1 Positive (1% <= X < 25%) PDL1 Positive (25% <= X < 50%) PDL1 Positive (>= 50%) None Systemic Treatment-Naive

ALK EGFR

8 main criterias to confirm

Bristol-Myers Squibb

Early Access Lung cancer

Accès précoce pré-AMM– IMFINZI (durvalumab)

SCLC (Small Cell Lung Cancer) Localized Locally Advanced None Chemotherapy Radiotherapy Chemotherapy Radiotherapy

7 main criterias to confirm

AstraZeneca

Phase 3 Kidney cancer

#NCT06364631

[CARE1] Etude de plateforme randomisée de première ligne pour optimiser le traitement chez les patients atteints de carcinome rénal métastatique

Clear cell carcinoma Metastatic None 0 1 or 2 Systemic Treatment-Naive

7 main criterias to confirm

Centre Hospitalier Régional Universitaire de Tours (Tours)

Gustave Roussy, Campus du cancer, Grand Paris

Phase 3 Lung cancer

#NCT05899608

[HARMONi-3] Étude clinique de l'IVONESCIMAB pour le traitement de première intention des patients atteints d'un CPNPC épidermoïde métastatique

NSCLC (Non-Small Cell Lung Cancer) Squamous NSCLC Metastatic Systemic Treatment-Naive

ALK EGFR ROS-1

8 main criterias to confirm

Centre Hospitalier Régional Universitaire de Tours (Tours)

Summit Therapeutics

Phase 3 Prostate cancer

#NCT06120491

[EvoPAR-PR01] AZD5305 vs placebo chez les hommes atteints d'un cancer de la prostate métastatique sensible à la castration recevant de nouveaux agents hormonaux choisis par le médecin

Metastatic Hormone-sensitive Other mutation Surgery Radiotherapy Systemic Treatment-Naive

8 main criterias to confirm

Centre Hospitalier Régional Universitaire de Tours (Tours)

AstraZeneca

Phase 3 Lung cancer

#NCT05920356

[CodeBreaK 202] Etude évaluant l'association du SOTORASIB/chimiothérapie double par PLATINE par rapport à l'association PEMBROLIZUMAB/chimiothérapie double par PLATINE en première ligne chez les participants atteints d'un cancer du poumon non à petites cellules non squameux de stade IV ou de stade avancé IIIB/C

NSCLC (Non-Small Cell Lung Cancer) Non-squamous NSCLC Locally Advanced Metastatic KRAS G12C PDL1 Negative (< 1%) None Systemic Treatment-Naive

Targeted therapy Immunotherapy Chemotherapy Targeted therapy Car-T Bispecific T-cell engager antibodies Antibody Drug Conjugates (ADC)

11 main criterias to confirm

Centre Hospitalier Régional Universitaire de Tours (Tours)

Amgen