Cancer clinical trials in the region Auvergne-Rhône-Alpes

332 currently recruiting clinical trials

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Phase 2 Breast cancer #NCT05973864

[CAPPA] CAPECITABINE et PEMBROLIZUMAB chez les patientes atteintes d'un cancer du sein triple négatif après chimio-immunothérapie et chirurgie

HER2 Negative HR Negative Localized None Systemic Treatment-Naive

Surgery Immunotherapy Chemotherapy

Centre Léon Bérard (Lyon)

UNICANCER

Phase 2 Bladder / Urinary Tract / Urethral cancer #NCT04617756

[iNDUCT] Etude sur le DURVALUMAB + chimiothérapie néoadjuvante dans le traitement du carcinome urothélial des voies supérieures à haut risque

Upper excretory tract cancer Urothelial carcinoma Localized None Systemic Treatment-Naive

Surgery

Hôpital Lyon Sud - Hospices Civils de Lyon (Pierre-Bénite)

Centre Hospitalier Universitaire de Nîmes

Phase 2 Lung cancer #NCT05742607

[MATISSE] IPH5201 et DURVALUMAB chez les patients atteints d'un cancer du poumon non à petites cellules résécable

NSCLC (Non-Small Cell Lung Cancer) Localized None Systemic Treatment-Naive

ALK EGFR Immunotherapy Targeted therapy

Centre Léon Bérard (Lyon)

Innate Pharma

Phase 1 / Phase 2 Colon cancer Rectal cancer #NCT06923761 #2023-504845-30-00

[EMITT-1] Essai de ciblage de l'immunopeptidome médié par ERAP - 1

Module 2 Partie D cancer colorectal pMMR/MSS

Locally Advanced Metastatic MSS/pMMR 1 2 3 or more

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Grey Wolf Therapeutics

Phase 1 / Phase 2 Lung cancer Bladder / Urinary Tract / Urethral cancer Stomach and esophageal cancer #NCT06923761 #2023-504845-30-00

[EMITT-1] Essai de ciblage de l'immunopeptidome médié par ERAP - 1

Module 2 Cohorte 3 Tumeurs solides avec un TMB médian modéré à élevé

NSCLC (Non-Small Cell Lung Cancer) Stomach Oesogastric junction Esophagus Invasive bladder cancer Adenocarcinoma Squamous cell carcinoma Urothelial carcinoma Locally Advanced Metastatic 1 2 Immunotherapy

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Grey Wolf Therapeutics

Phase 1 / Phase 2 Liver and bile duct cancer #NCT06923761 #2023-504845-30-00

[EMITT-1] Essai de ciblage de l'immunopeptidome médié par ERAP - 1

Module 2 Cohorte 2 carcinome hépatocellulaire

Hepatocellular carcinoma Locally Advanced Metastatic Unhealthy A 1 2 Immunotherapy

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Grey Wolf Therapeutics

Phase 1 / Phase 2 Breast cancer Lung cancer Prostate cancer Colon cancer Rectal cancer Anal cancer Kidney cancer Pancreas cancer Liver and bile duct cancer Bladder / Urinary Tract / Urethral cancer Stomach and esophageal cancer Endometrial cancer Ovarian / Fallopian tubes / Peritoneum cancer #NCT06923761 #2023-504845-30-00

[EMITT-1] Essai de ciblage de l'immunopeptidome médié par ERAP - 1

Module 1 (Partie A, B, C) et module 2 (parties A et B) Tumeurs solides avancées

Locally Advanced Metastatic 1 2 3 or more

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Grey Wolf Therapeutics

Phase 1 / Phase 2 Prostate cancer #NCT06863272

[IDeate-Prostate02] Étude clinique sur les combinaisons de traitements à base d'ifinatamab deruxtecan ou en monothérapie pour traiter le cancer de la prostate métastatique résistant à la castration (mCRPC)

Adenocarcinoma Metastatic Castration-resistant 1 2 Targeted therapy Hormone therapy

Systemic Treatment-Naive Chemotherapy

Hôpital Lyon Sud - Hospices Civils de Lyon (Pierre-Bénite)

Merck Sharp & Dohme LLC

Phase 1 / Phase 2 Lung cancer #NCT06567015 #2023-510203-21-00

Étude de première administration chez l'homme (FIH) du STX-241 dans le CBNPC localement avancé ou métastatique résistant aux ITK de l'EGFR

NSCLC (Non-Small Cell Lung Cancer) Locally Advanced Metastatic EGFR 1 2 3 or more

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Laboratoires Pierre Fabre

Phase 1 / Phase 2 Bladder / Urinary Tract / Urethral cancer #NCT04752722 #2024-512900-20-00

[LEGEND] EG-70 chez les patients atteints de cancer de la vessie non invasif réfractaire au BCG et à haut risque traités incomplètement par le BCG ou naïfs au BCG

Phase 2

Non-invasive bladder cancer Urothelial carcinoma Localized None 1 Systemic Treatment-Naive Immunotherapy

Hôpital de la Croix Rousse - Hospices Civils de Lyon (Lyon)

enGene, Inc.