Cancer clinical trials in the region Grand Est
284 currently recruiting clinical trials
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Phase 3
Acute leukemia
#NCT07007312
#2025-521314-25-00
Etude de thérapie intensive
Required histologic types
Acute myeloid leukemia (AML)
Required genetic anomalies
KMT2A
NPM1
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded genetic anomalies
BCR-ABL
11 recruiting sites
Kura Oncologie, Inc.
Phase 3
Penile cancer and germ cell tumors
#NCT05874063
#2022-502426-41-00
Required histologic types
Germ cell tumor
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Required IGCCCG prognostic scores
Good prognosis
Intermediate prognosis
18 recruiting sites
Gustave Roussy, Campus du cancer, Grand Paris
Phase 3
Head and neck cancer
#NCT06525220
#2023-510323-30-00
Required histologic types
Oral cavity
Oropharynx
Hypopharynx
Larynx
Required histologic sub types
Squamous cell carcinoma
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Required CPS scores
CPS Positive (1 <= X < 20)
CPS Positive (X >= 20)
14 recruiting sites
Merus
Phase 3
Breast cancer
#NCT07237256
#2025-520979-13-00
Required HER2 statuses
HER2 Negative
Required HR statuses
HR Positive
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Surgery
Excluded previous treatments at localized stage
Chemotherapy
Targeted therapy
16 recruiting sites
UNICANCER
Phase 3
Lymphoma
#NCT06717347
#2024-515566-13-00
Required histologic types
B cell lymphoma
Required histologic sub types
Large B cell lymphoma
Required central nervous system lesions
None
Treated / Controled
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
14 recruiting sites
Merck Sharp & Dohme LLC
Phase 3
Lung cancer
#NCT06472245
#2023-509340-10-00
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Immunotherapy
Excluded genetic anomalies
ALK
EGFR
ROS-1
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
29 recruiting sites
OSE Immunotherapeutics
Phase 3
Prostate cancer
#NCT07164443
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic Castration-resistant
Required number of previous lines of therapy for current stage of disease
3 or more
Required previous treatments at advanced or metastatic stage
Chemotherapy
Targeted therapy
Hormone therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
11 recruiting sites
Janssen
Phase 3
Sarcoma and GIST
#NCT04307277
#2024-515384-62-00
Required histologic types
Soft tissue sarcoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Surgery
Required sarcoma grades
Grade 1
Grade 2
Grade 3
19 recruiting sites
Institut Claudius Regaud
Phase 3
Colon cancer
Rectal cancer
#NCT02885753
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
85 recruiting sites
Fédération Francophone de Cancérologie Digestive
Phase 3
Acute leukemia
#NCT04307576
#2022-501050-11-01
Required histologic types
Acute lymphoblastic leukemia (ALL)
Required histologic sub types
T-cell (T-ALL)
B-cell (B-ALL)
Required genetic anomalies
MYC
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
28 recruiting sites
Karolinska University Hospital