Cancer clinical trials in the region Grand Est
291 currently recruiting clinical trials
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Phase 3
Lung cancer
#NCT06472245
#2023-509340-10-00
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Immunotherapy
Excluded genetic anomalies
ALK
EGFR
ROS-1
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
29 recruiting sites
OSE Immunotherapeutics
Phase 3
Colon cancer
Rectal cancer
#NCT02885753
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
79 recruiting sites
Fédération Francophone de Cancérologie Digestive
Phase 3
Acute leukemia
#NCT04307576
#2022-501050-11-01
Required histologic types
Acute lymphoblastic leukemia (ALL)
Required histologic sub types
T-cell (T-ALL)
B-cell (B-ALL)
Required genetic anomalies
MYC
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
28 recruiting sites
Karolinska University Hospital
Phase 3
Lung cancer
#NCT04790253
Required histologic types
SCLC (Small Cell Lung Cancer)
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Chemotherapy
Required previous treatments at advanced or metastatic stage
Chemotherapy
25 recruiting sites
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 3
Colon cancer
#NCT02355379
Required histologic sub types
Adenocarcinoma
Required disease stage
Locally Advanced
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Surgery
Excluded previous treatments at advanced or metastatic stage
Chemotherapy
112 recruiting sites
Fédération Francophone de Cancérologie Digestive
Phase 3
Prostate cancer
#NCT06629779
#2024-511652-40-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic Castration-resistant
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
10 recruiting sites
Pfizer
Phase 3
Colon cancer
Rectal cancer
#NCT04120701
#2024-515297-27-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Localized
Locally Advanced
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Surgery
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Surgery
Excluded previous treatments at localized stage
Chemotherapy
Radiotherapy
Excluded previous treatments at advanced or metastatic stage
Chemotherapy
Radiotherapy
123 recruiting sites
CHU Dijon
Phase 3
Lung cancer
#NCT05920356
#2022-501863-41-00
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required histologic sub types
Non-squamous NSCLC
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
KRAS G12C
Required PDL1 statuses
PDL1 Negative (< 1%)
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
Chemotherapy
Targeted therapy
Car-T
Bispecific T-cell engager antibodies
Antibody Drug Conjugates (ADC)
28 recruiting sites
Amgen
Phase 3
Head and neck cancer
#NCT04747054
Required histologic types
Oral cavity
Oropharynx
Hypopharynx
Larynx
Other
Required histologic sub types
Squamous cell carcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Required CPS scores
CPS Positive (1 <= X < 20)
CPS Positive (X >= 20)
20 recruiting sites
UNICANCER
Phase 3
Head and neck cancer
#NCT06256588
#2023-508613-17-00
Required histologic types
Oral cavity
Oropharynx
Hypopharynx
Larynx
Required histologic sub types
Squamous cell carcinoma
Required disease stage
Locally Advanced
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Radiochemotherapy
Required CPS scores
CPS Positive (1 <= X < 20)
CPS Positive (X >= 20)
Excluded previous treatments at advanced or metastatic stage
Surgery
Immunotherapy
Targeted therapy
Radiotherapy
6 recruiting sites
GlaxoSmithKline