Cancer clinical trials in the region Auvergne-Rhône-Alpes

319 currently recruiting clinical trials

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Phase 2 Endometrial cancer #NCT06172478 #2023-507641-29-00

[HERTHENA-PanTumor01] Etude sur HER3-DXd chez des sujets atteints de tumeurs solides localement avancées ou métastatiques

Endometrioid adenocarcinoma Serous adenocarcinoma Clear cell carcinoma Dedifferentiated and undifferentiated endometrial ... Carcinosarcoma Locally Advanced Metastatic 1 2 3 or more Immunotherapy Chemotherapy

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Daiichi Sankyo

Phase 2 Endometrial cancer #NCT05489211 #2023-509436-26-00

[TROPION-PanTumor03] Étude du DATO-DXD en monothérapie et en association avec des agents anticancéreux chez des patients atteints de tumeurs solides avancées

Locally Advanced Metastatic 1 2 3 or more

Antibody Drug Conjugates (ADC) Systemic Treatment-Naive Antibody Drug Conjugates (ADC)

Centre Léon Bérard (Lyon)

AstraZeneca

Phase 2 Lymphoma #NCT06806033 #2024-516791-15-00

Étude visant à évaluer l'optimisation du profil du syndrome de libération de cytokines lors du traitement par GLOFITAMAB en association avec la GEMCITABINE plus l'OXALIPLATINE chez les participants atteints d'un lymphome diffus à grandes cellules B récidivant/réfractaire

B cell lymphoma Large B cell lymphoma None Treated / Controled 1 2 3 or more

Systemic Treatment-Naive Bispecific T-cell engager antibodies Allogeneic stem cell transplant

Centre Hospitalier Universitaire de Grenoble (La Tronche)

Hoffmann-La Roche

Phase 2 Bladder / Urinary Tract / Urethral cancer #NCT06660654 #2024-513307-13-00

[REJOICE-PanTumor01] Étude du RALUDOTATUG DERUXTECAN chez des participants atteints de tumeurs solides avancées/métastatiques

Invasive bladder cancer Upper excretory tract cancer Urethral cancer Locally Advanced Metastatic 1 2 3 or more Immunotherapy

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Daiichi Sankyo

Phase 2 Lymphoma #NCT04802590 #2024-512634-15-00

Étude sur l'IBRUTINIB + un anticorps anti-CD20 et le VENETOCLAX chez des patients atteints de lymphome à cellules du manteau non traité

B cell lymphoma Mantel cell lymphoma None CD20 > 60 ml/min 50-60 ml/min None Systemic Treatment-Naive

CHU Saint-Étienne (Saint-Priest-en-Jarez), Hôpital Lyon Sud - Hospices Civils de Lyon (Pierre-Bénite), Centre Léon Bérard (Lyon), Centre Hospitalier Universitaire de Grenoble (La Tronche), Centre Hospitalier Universitaire de Clermont Ferrand (Clermont-Ferrand) (and 1 more...)

The Lymphoma Academic Research Organisation (LYSARC)

Phase 2 Endometrial cancer #NCT06660654 #2024-513307-13-00

[REJOICE-PanTumor01] Étude du RALUDOTATUG DERUXTECAN chez des participants atteints de tumeurs solides avancées/métastatiques

Locally Advanced Metastatic 1 2 3 or more Immunotherapy Chemotherapy

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Daiichi Sankyo

Phase 2 Lung cancer #NCT05732831 #2022-502645-99-00

Innocuité et tolérance du TNG462 chez les patients atteints de tumeurs solides avec suppression du gène MTAP

SCLC (Small Cell Lung Cancer) NSCLC (Non-Small Cell Lung Cancer) Mesothelium Locally Advanced Metastatic MTAP 1 2 3 or more

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Tango Therapeutics

Phase 2 Lymphoma #NCT05963074 #2023-504044-34-00

[TAILOR] Étude visant à personnaliser les schémas thérapeutiques à base d'IBRUTINIB pour les participants atteints de leucémie lymphoïde chronique/lymphome lymphocytaire à petits lymphocytes non traités auparavant

B cell lymphoma Lymphocytic lymphoma None None Systemic Treatment-Naive

Hôpital Lyon Sud - Hospices Civils de Lyon (Pierre-Bénite)

Janssen

Phase 2 Pancreas cancer #NCT06172478 #2023-507641-29-00

[HERTHENA-PanTumor01] Etude sur HER3-DXd chez des sujets atteints de tumeurs solides localement avancées ou métastatiques

Adenocarcinoma Locally Advanced Metastatic 1

Systemic Treatment-Naive

Centre Léon Bérard (Lyon)

Daiichi Sankyo

Phase 2 Breast cancer #NCT05215106 #2024-512082-14-00

[POP-DURVA] Étude du DURVALUMAB (MEDI 4736) préopératoire de courte durée chez des patientes atteintes d'un cancer du sein triple négatif de petite taille

HER2 Negative HR Negative Localized None Systemic Treatment-Naive

Surgery Immunotherapy Chemotherapy Targeted therapy Car-T Bispecific T-cell engager antibodies Antibody Drug Conjugates (ADC) Radiotherapy

Centre Léon Bérard (Lyon)

Gustave Roussy, Campus du cancer, Grand Paris