Clinical trials for Brain tumors / Central nervous system tumors
61 currently recruiting clinical trials
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Early Access
Brain tumors / Central nervous system tumors
Required histologic types
Gliomas
Required histologic sub types
Astrocytoma grade II
Oligodendroglioma grade II
Required genetic anomalies
IDH1/2
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Surgery
1 recruiting site
Servier
Phase 3
Brain tumors / Central nervous system tumors
#NCT05902169
#2023-505829-14-00
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
1
Required previous treatments
Surgery
Immunotherapy
Chemotherapy
Radiotherapy
Excluded genetic anomalies
BRAF
IDH1/2
NTRK-1/2/3
Excluded previous treatments
Systemic Treatment-Naive
3 recruiting sites
CarThera
Phase 3
Breast cancer
Lung cancer
Prostate cancer
Colon cancer
Rectal cancer
Anal cancer
Kidney cancer
Pancreas cancer
Liver and bile duct cancer
Bladder / Urinary Tract / Urethral cancer
Stomach and esophageal cancer
Endometrial cancer
Ovarian / Fallopian tubes / Peritoneum cancer
Head and neck cancer
Sarcoma and GIST
Thymus cancer
Penile cancer and germ cell tumors
Cervical / Vulvar / Vaginal cancer
Small intestine and appendix cancer
Thyroid and adrenal gland cancer
Brain tumors / Central nervous system tumors
Skin cancer
#NCT06471465
#2024-510893-25-00
Required previous treatments
Radiotherapy
9 recruiting sites
Institut de Cancérologie de l'Ouest
Phase 3
Lymphoma
Brain tumors / Central nervous system tumors
#NCT07104032
#2025-523389-26-00
Required histologic types
B cell lymphoma
Other primary CNS tumor
Required histologic sub types
Primary cerebral lymphoma
Primary CNS lymphoma
Required number of previous lines of therapy
2
3 or more
Required previous treatments
Chemotherapy
Excluded previous treatments
Systemic Treatment-Naive
Targeted therapy
Other targeted therapy
2 recruiting sites
Ono Pharmaceutical Co. Ltd.
Phase 3
Brain tumors / Central nervous system tumors
#NCT06809322
#2024-519404-27-00
Required histologic types
Gliomas
Required histologic sub types
Astrocytoma grade II
Astrocytoma grade III
Required genetic anomalies
IDH1/2
Required number of previous lines of therapy
None
Required previous treatments
Surgery
Radiochemotherapy
Excluded previous treatments
Systemic Treatment-Naive
2 recruiting sites
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 3
Brain tumors / Central nervous system tumors
#NCT05512403
#2022-501688-42-00
Required histologic types
Gliomas
Required histologic sub types
Low-grade glioma
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
1 recruiting site
Hôpital central, Nancy, France
Phase 3
Brain tumors / Central nervous system tumors
#NCT05904119
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
1
Required previous treatments
Surgery
Radiochemotherapy
Excluded genetic anomalies
IDH1/2
Excluded previous treatments
Systemic Treatment-Naive
10 recruiting sites
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 3
Brain tumors / Central nervous system tumors
#NCT05476939
#2014-001929-32
Phase inclusion DIPG
Required histologic types
Gliomas
Required histologic sub types
Diffuse midline glioma grade IV
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded previous treatments
Chemotherapy
Radiotherapy
32 recruiting sites
Gustave Roussy, Campus du cancer, Grand Paris
Phase 3
Brain tumors / Central nervous system tumors
#NCT05476939
#2014-001929-32
Phase inclusion - gliomes diffus de la ligne médiane non-DIPG
Required histologic types
Gliomas
Required histologic sub types
Diffuse midline glioma grade IV
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded previous treatments
Chemotherapy
Radiotherapy
33 recruiting sites
Gustave Roussy, Campus du cancer, Grand Paris
Phase 3
Brain tumors / Central nervous system tumors
#NCT04702581
Required histologic types
Gliomas
Required histologic sub types
Oligodendroglioma grade II
Required genetic anomalies
IDH1/2
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Surgery
Excluded previous treatments
Chemotherapy
Radiotherapy
14 recruiting sites
Hospices Civils de Lyon