Clinical trials for Brain tumors / Central nervous system tumors

50 currently recruiting clinical trials

Phase 3 Brain tumors / Central nervous system tumors #NCT06556563 #2024-513550-30-00
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
None
Required previous treatments
Surgery Chemotherapy Radiotherapy Radiochemotherapy
Excluded previous treatments
Systemic Treatment-Naive Immunotherapy
5 recruiting sites
NovoCure GmbH
Phase 3 Brain tumors / Central nervous system tumors #NCT06809322 #2024-519404-27-00
Required histologic types
Gliomas
Required histologic sub types
Astrocytoma grade II Astrocytoma grade III
Required genetic anomalies
IDH1/2
Required number of previous lines of therapy
None
Required previous treatments
Surgery Radiochemotherapy
Excluded previous treatments
Systemic Treatment-Naive
1 recruiting site
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 3 Brain tumors / Central nervous system tumors #NCT06388733 #2024-513077-48-00
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded genetic anomalies
IDH1/2
Excluded previous treatments
Chemotherapy Radiotherapy Radiochemotherapy TTFields Other targeted therapy
10 recruiting sites
Ivy Brain Tumor Center
Phase 3 Brain tumors / Central nervous system tumors #NCT05902169 #2023-505829-14-00
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
1
Required previous treatments
Surgery Immunotherapy Chemotherapy Radiotherapy
Excluded genetic anomalies
BRAF IDH1/2 NTRK-1/2/3
Excluded previous treatments
Systemic Treatment-Naive
3 recruiting sites
CarThera
Phase 3 Brain tumors / Central nervous system tumors #NCT05512403 #2022-501688-42-00
Required histologic types
Gliomas
Required histologic sub types
Low-grade glioma
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
1 recruiting site
Hôpital central, Nancy, France
Phase 3 Brain tumors / Central nervous system tumors #NCT05904119
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
1
Required previous treatments
Surgery Radiochemotherapy
Excluded genetic anomalies
IDH1/2
Excluded previous treatments
Systemic Treatment-Naive
10 recruiting sites
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 3 Brain tumors / Central nervous system tumors #NCT05476939 #2014-001929-32
Required histologic types
Gliomas
Required histologic sub types
Diffuse midline glioma grade IV
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded previous treatments
Chemotherapy Radiotherapy
33 recruiting sites
Gustave Roussy, Campus du cancer, Grand Paris
Phase 3 Brain tumors / Central nervous system tumors #NCT05476939 #2014-001929-32
Phase inclusion - gliomes diffus de la ligne médiane non-DIPG
Required histologic types
Gliomas
Required histologic sub types
Diffuse midline glioma grade IV
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Excluded previous treatments
Chemotherapy Radiotherapy
33 recruiting sites
Gustave Roussy, Campus du cancer, Grand Paris
Phase 3 Brain tumors / Central nervous system tumors #NCT04702581
Required histologic types
Gliomas
Required histologic sub types
Oligodendroglioma grade II
Required genetic anomalies
IDH1/2
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive Surgery
Excluded previous treatments
Chemotherapy Radiotherapy
13 recruiting sites
Hospices Civils de Lyon
Phase 2 Brain tumors / Central nervous system tumors #NCT06326190 #2024-513443-93-00
Required histologic types
Other primary CNS tumor
Required histologic sub types
Meningioma
Required number of previous lines of therapy
1 2 3 or more
Required previous treatments
Systemic Treatment-Naive Surgery Radiotherapy
7 recruiting sites
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer