Clinical trials for Sarcoma and GIST
86 currently recruiting clinical trials
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Phase 3
Sarcoma and GIST
#NCT07218926
#2025-522229-37-00
Required histologic types
GIST
Required disease stage
Locally Advanced
Metastatic
Required genetic anomalies
KIT
PDGFRA
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
8 recruiting sites
GlaxoSmithKline
Phase 3
Sarcoma and GIST
#NCT04307277
#2024-515384-62-00
Required histologic types
Soft tissue sarcoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Surgery
Required sarcoma grades
Grade 1
Grade 2
Grade 3
20 recruiting sites
Institut Claudius Regaud
Phase 3
Sarcoma and GIST
#NCT04031677
Required histologic types
Soft tissue sarcoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Surgery
3 recruiting sites
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 3
Sarcoma and GIST
#NCT04757337
#2018-000542-20
Required histologic types
Soft tissue sarcoma
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
1 recruiting site
UNICANCER
Phase 3
Sarcoma and GIST
#NCT03805022
#2018-000186-36
Required histologic types
Soft tissue sarcoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
6 recruiting sites
Institut Bergonié
Phase 3
Sarcoma and GIST
#NCT06127407
#2023-508507-20-00
Required histologic types
Bone sarcoma
Required histologic sub types
Chondrosarcoma
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
None
1
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Chemotherapy
Targeted therapy
8 recruiting sites
Phase 3
Sarcoma and GIST
#NCT04650984
#2024-512789-32-00
Required histologic types
Soft tissue sarcoma
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Chemotherapy
4 recruiting sites
Philogène SpA
Phase 3
Lung cancer
Colon cancer
Rectal cancer
Pancreas cancer
Sarcoma and GIST
#NCT06332274
#2023-503316-33-00
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Soft tissue sarcoma
Required disease stage
Localized
Locally Advanced
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Surgery
Chemotherapy
Required previous treatments at advanced or metastatic stage
Surgery
Chemotherapy
Excluded genetic anomalies
EGFR
Excluded previous treatments at localized stage
Immunotherapy
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
4 recruiting sites
Gustave Roussy, Campus du cancer, Grand Paris
Phase 2
Breast cancer
Lung cancer
Prostate cancer
Colon cancer
Rectal cancer
Anal cancer
Kidney cancer
Pancreas cancer
Liver and bile duct cancer
Bladder / Urinary Tract / Urethral cancer
Stomach and esophageal cancer
Endometrial cancer
Ovarian / Fallopian tubes / Peritoneum cancer
Head and neck cancer
Sarcoma and GIST
Thymus cancer
Penile cancer and germ cell tumors
Cervical / Vulvar / Vaginal cancer
Small intestine and appendix cancer
#NCT07303387
#2024-519788-16-00
Efficacité et innocuité du valémétostat chez les patients atteints de tumeurs solides sélectionnées.
Cohorte 1.D (Défience PBRM1)
Required disease stage
Metastatic
Metastatic Castration-resistant
Required genetic anomalies
Other mutation
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
1 recruiting site
Gustave Roussy, Campus du cancer, Grand Paris
Phase 2
Sarcoma and GIST
#NCT05182164
#2023-509496-16-00
Sarcome d’Ewing
Required histologic types
Bone sarcoma
Required histologic sub types
Ewing tumor
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Immunotherapy
6 recruiting sites
Institut Bergonié, Merck Sharp & Dohme LLC