Clinical trials for Sarcoma and GIST

84 currently recruiting clinical trials

Phase 3 Sarcoma and GIST #NCT07218926 #2025-522229-37-00
Required histologic types
GIST
Required disease stage
Locally Advanced Metastatic
Required genetic anomalies
KIT PDGFRA
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
8 recruiting sites
GlaxoSmithKline
Phase 3 Sarcoma and GIST #NCT04307277 #2024-515384-62-00
Required histologic types
Soft tissue sarcoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Surgery
Required sarcoma grades
Grade 1 Grade 2 Grade 3
20 recruiting sites
Institut Claudius Regaud
Phase 3 Sarcoma and GIST #NCT04031677
Required histologic types
Soft tissue sarcoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Surgery
3 recruiting sites
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 3 Sarcoma and GIST #NCT04757337 #2018-000542-20
Required histologic types
Soft tissue sarcoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
1 recruiting site
UNICANCER
Phase 3 Sarcoma and GIST #NCT03805022 #2018-000186-36
Required histologic types
Soft tissue sarcoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
6 recruiting sites
Institut Bergonié
Phase 3 Sarcoma and GIST #NCT06127407 #2023-508507-20-00
Required histologic types
Bone sarcoma
Required histologic sub types
Chondrosarcoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None 1
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive Chemotherapy Targeted therapy
8 recruiting sites
Phase 3 Sarcoma and GIST #NCT04650984 #2024-512789-32-00
Required histologic types
Soft tissue sarcoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Chemotherapy
4 recruiting sites
Philogène SpA
Phase 3 Lung cancer Colon cancer Rectal cancer Pancreas cancer Sarcoma and GIST #NCT06332274 #2023-503316-33-00
Required histologic types
NSCLC (Non-Small Cell Lung Cancer) Soft tissue sarcoma
Required disease stage
Localized Locally Advanced
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Surgery Chemotherapy
Required previous treatments at advanced or metastatic stage
Surgery Chemotherapy
Excluded genetic anomalies
EGFR
Excluded previous treatments at localized stage
Immunotherapy
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
4 recruiting sites
Gustave Roussy, Campus du cancer, Grand Paris
Phase 2 Sarcoma and GIST #NCT05182164 #2023-509496-16-00
Required histologic types
Bone sarcoma
Required histologic sub types
Ewing tumor
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1 2 3 or more
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive Immunotherapy
6 recruiting sites
Institut Bergonié, Merck Sharp & Dohme LLC
Phase 2 Sarcoma and GIST #NCT05182164 #2023-509496-16-00
Required histologic types
Bone sarcoma
Required histologic sub types
Osteosarcoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1 2 3 or more
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive Immunotherapy
6 recruiting sites
Institut Bergonié