Cancer clinical trials in the region Grand Est
286 currently recruiting clinical trials
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Whether you are a patient or a doctor, create an account to find and apply for the most relevant clinical trials:
Phase 3
Skin cancer
#NCT06692556
Required histologic types
Squamous cell carcinoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Surgery
Excluded previous treatments at localized stage
Radiotherapy
12 recruiting sites
Centre Léon Bérard
Phase 3
Skin cancer
#NCT05078047
Cancer de Merkel, mélanome, carcinome basocellulaire ou carcinome épidermoïde de la peau
Required histologic types
Melanoma
Basal cell carcinoma
Squamous cell carcinoma
Merkel cell carcinoma
Required disease stage
Locally Advanced
Metastatic
Required previous treatments at advanced or metastatic stage
Immunotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
24 recruiting sites
UNICANCER
Phase 3
Breast cancer
#NCT06103864
#2023-503675-24-00
Required HER2 statuses
HER2 Negative
Required HR statuses
HR Negative
Required disease stage
Metastatic
Required PDL1 statuses
PDL1 Positive (1% <= X < 25%)
PDL1 Positive (25% <= X < 50%)
PDL1 Positive (>= 50%)
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
8 recruiting sites
AstraZeneca
Phase 3
Breast cancer
#NCT06103864
#2023-503675-24-00
Required HER2 statuses
HER2 Negative
Required HR statuses
HR Negative
Required disease stage
Locally Advanced
Required PDL1 statuses
PDL1 Positive (1% <= X < 25%)
PDL1 Positive (25% <= X < 50%)
PDL1 Positive (>= 50%)
8 recruiting sites
AstraZeneca
Phase 3
Colon cancer
Rectal cancer
#NCT07228832
#2025-521587-35-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded genetic anomalies
BRAF
MSI/dMMR
Excluded previous treatments at localized stage
Immunotherapy
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
Targeted therapy
9 recruiting sites
Summit Therapeutics
Phase 3
Lymphoma
CLL & Richter's syndrome
#NCT06104566
#2023-508005-24-00
Required histologic types
B cell lymphoma
CLL (Chronic Lymphocytic Leukemia)
Required histologic sub types
Lymphocytic lymphoma
Required number of previous lines of therapy
1
Required previous treatments
Targeted therapy
Excluded previous treatments
Systemic Treatment-Naive
12 recruiting sites
Ascentage Pharma Group Inc.
Phase 3
Liver and bile duct cancer
#NCT07221253
#2025-523085-24-00
Required histologic sub types
Intrahepatic cholangiocarcinoma
Extrahepatic cholangiocarcinoma
Required disease stage
Locally Advanced
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at advanced or metastatic stage
Immunotherapy
4 recruiting sites
AstraZeneca
Phase 3
Prostate cancer
#NCT06764485
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic Castration-resistant
Required number of previous lines of therapy for current stage of disease
1
2
3 or more
Required previous treatments at advanced or metastatic stage
Hormone therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
8 recruiting sites
Celgene
Phase 3
Brain tumors / Central nervous system tumors
#NCT05512403
#2022-501688-42-00
Required histologic types
Gliomas
Required histologic sub types
Low-grade glioma
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
1 recruiting site
Hôpital central, Nancy, France
Phase 3
Brain tumors / Central nervous system tumors
#NCT05904119
Required histologic types
Gliomas
Required histologic sub types
Glioblastoma
Required number of previous lines of therapy
1
Required previous treatments
Surgery
Radiochemotherapy
Excluded genetic anomalies
IDH1/2
Excluded previous treatments
Systemic Treatment-Naive
10 recruiting sites
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer