Cancer clinical trials in the region Île-de-France

684 currently recruiting clinical trials
Region Île-de-France

Phase 3 Lung cancer #NCT04613596 #2023-508922-83-00
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required disease stage
Locally Advanced Metastatic
Required genetic anomalies
KRAS G12C
Required PDL1 statuses
PDL1 Positive (>= 50%)
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
16 recruiting sites
Mirati Thérapeutique Inc.
Phase 3 Lung cancer #NCT07222566 #2025-523461-17-01
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required histologic sub types
Squamous NSCLC Non-squamous NSCLC
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded genetic anomalies
ALK BRAF EGFR MET NTRK-1/2/3 RET ROS-1
Excluded previous treatments at advanced or metastatic stage
Immunotherapy Targeted therapy
4 recruiting sites
Pfizer
Phase 3 Myelodysplastic Syndromes (MDS) and Myeloproliferative Neoplasms (MPN) #NCT06465953 #2023-510155-37
Required histologic types
Myelodysplastic syndromes (MDS)
Required histologic sub types
MDS de novo Secondary MDS
Required genetic anomalies
IDH1/2
Required number of previous lines of therapy
None
Required IPSS-M prognostic scores
Low Moderately low Moderately high High Very high
Excluded previous treatments
Chemotherapy Allogeneic stem cell transplant
6 recruiting sites
Servier
Phase 3 Small intestine and appendix cancer #NCT06878664 #2024-517921-14-00
Required histologic types
Jejunum cancer Ileum cancer
Required histologic sub types
Neuroendocrine tumor
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None 1
Required SSTR metabolic imaging statuses
SSTR Positive
Excluded previous treatments at advanced or metastatic stage
Radiotherapy
3 recruiting sites
Grupo Espanol de Tumores Neuroendocrinos
Phase 3 Head and neck cancer #NCT06496178 #2023-510322-32-00
Required histologic types
Oral cavity Oropharynx Hypopharynx Larynx
Required histologic sub types
Squamous cell carcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Immunotherapy Chemotherapy
14 recruiting sites
Merus
Phase 3 Myelodysplastic Syndromes (MDS) and Myeloproliferative Neoplasms (MPN) #NCT06641414 #2024-517247-31-00
Required histologic types
Myelodysplastic syndromes (MDS)
Required histologic sub types
MDS de novo
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
Required IPSS-R prognostic scores
High Very high
Required IPSS-M prognostic scores
High Very high
Excluded previous treatments
Allogeneic stem cell transplant
1 recruiting site
Ascentage Pharma Group Inc.
Phase 3 Head and neck cancer #NCT06129864
Required histologic types
Oral cavity Oropharynx Hypopharynx Larynx
Required histologic sub types
Squamous cell carcinoma
Required disease stage
Locally Advanced
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Radiochemotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive Surgery Radiotherapy
8 recruiting sites
AstraZeneca
Phase 3 Kidney cancer #NCT07011719 #2024-515023-11-00
Required histologic types
Clear cell carcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Immunotherapy
9 recruiting sites
Arcus Biosciences
Phase 3 Lymphoma #NCT06091865 #2022-502785-25-00
Required histologic types
B cell lymphoma
Required histologic sub types
Large B cell lymphoma
Required central nervous system lesions
None
Required immunophenotypic profiles
CD20
Required number of previous lines of therapy
None
Required previous treatments
Systemic Treatment-Naive
18 recruiting sites
Regeneron Pharmaceuticals
Phase 3 Lymphoma #NCT06091865 #2022-502785-25-00
Required histologic types
B cell lymphoma
Required histologic sub types
Large B cell lymphoma
Required central nervous system lesions
None
Required immunophenotypic profiles
CD20
Required number of previous lines of therapy
1 2 3 or more
Excluded previous treatments
Systemic Treatment-Naive
18 recruiting sites
Regeneron Pharmaceuticals