Cancer clinical trials in the region Île-de-France

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Phase 3 Breast cancer #NCT06760637

[FOURLIGHT-3] Étude du PF-07220060 avec le LETROZOLE chez des adultes atteints d'un cancer du sein RH-positif HER2-négatif n'ayant pas reçu de traitement anticancéreux pour une maladie avancée/métastatique

HER2 Negative HR Positive Locally Advanced Metastatic None Systemic Treatment-Naive

3 recruiting sites

Pfizer

Phase 3 Endometrial cancer #NCT06952504 #2024-519331-42-00

[TroFuse-033] Étude comparant le SACITUZUMAB TIRUMOTECANen association avec le PEMBROLIZUMAB et le pembrolizumab seul chez des participantes atteintes d'un cancer de l'endomètre pMMR

Endometrioid adenocarcinoma Serous adenocarcinoma Clear cell carcinoma Dedifferentiated and undifferentiated endometrial ... Locally Advanced Metastatic MSS/pMMR None Systemic Treatment-Naive

MSI/dMMR Immunotherapy Antibody Drug Conjugates (ADC) Immunotherapy Antibody Drug Conjugates (ADC)

10 recruiting sites

Merck Sharp & Dohme LLC

Phase 3 Ovarian / Fallopian tubes / Peritoneum cancer #NCT06824467 #2023-508015-23-00

[TroFuse-022] Étude visant à évaluer l'efficacité et l'innocuité du traitement par sacituzumab tirumotecan (MK-2870) par rapport au traitement standard chez les participantes atteintes d'un cancer de l'ovaire récurrent sensible au platine

Epithelial ovarian cancer Fallopian tube cancer Primary peritoneal cancer (PPC) Stage III Stage IV 1 2 Recurrence 6 months or more after platinum treatme... Chemotherapy Chemotherapy

Systemic Treatment-Naive Systemic Treatment-Naive

11 recruiting sites

Merck Sharp & Dohme LLC

Phase 3 Ovarian / Fallopian tubes / Peritoneum cancer #NCT06819007

[DESTINY-Ovarian01] Étude du trastuzumab deruxtecan associé au bévacizumab versus bévacizumab en monothérapie pour le traitement d'entretien de première ligne du cancer de l'ovaire exprimant HER2

Epithelial ovarian cancer Fallopian tube cancer Primary peritoneal cancer (PPC) Serous high grade carcinoma (HGSOC) Endometrioid carcinoma Clear cell carcinoma Mucinous carcinoma Other epithelial ovarian cancer Stage III Stage IV Locally Advanced Metastatic HER2 None Chemotherapy Targeted therapy

BRCA 1/2

10 recruiting sites

Daiichi Sankyo