Gustave Roussy

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Phase 2 Lung cancer #NCT06172478 #2023-507641-29-00
Cancer du poumon
Required histologic types
NSCLC (Non-Small Cell Lung Cancer)
Required histologic sub types
Non-squamous NSCLC
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Immunotherapy Chemotherapy
Excluded genetic anomalies
ALK BRAF EGFR HER2 KRAS G12C MET NTRK-1/2/3 RET ROS-1
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Gustave Roussy (Villejuif)
Daiichi Sankyo
Phase 2 Kidney cancer #NCT06783348 #2024-517899-38-00
Required histologic types
Clear cell carcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Immunotherapy Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Gustave Roussy (Villejuif)
EORTC - Organisation Européenne pour la Recherche et le Traitement du Cancer
Phase 2 Liver and bile duct cancer #NCT06218420
Required histologic sub types
Hepatocellular carcinoma
Required disease stage
Localized
Required liver status
Unhealthy
Required Child-Pugh scores
A B
Required number of previous lines of therapy for current stage of disease
None
Gustave Roussy (Villejuif)
Assistance Publique - Hôpitaux de Paris
Phase 2 Stomach and esophageal cancer #NCT06172478 #2023-507641-29-00
Carcinome épidermoïde de l’œsophage
Required histologic types
Esophagus
Required histologic sub types
Squamous cell carcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
2
Required previous treatments at advanced or metastatic stage
Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Gustave Roussy (Villejuif)
Daiichi Sankyo
Phase 2 Breast cancer #NCT06172478 #2023-507641-29-00
Cancer du sein
Required HER2 statuses
HER2 Negative
Required HR statuses
HR Positive
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Chemotherapy Targeted therapy Hormone therapy
Excluded genetic anomalies
ALK BRAF EGFR HER2 KRAS G12C MET NTRK-1/2/3 RET ROS-1
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Gustave Roussy (Villejuif)
Daiichi Sankyo
Phase 2 Pancreas cancer #NCT06172478 #2023-507641-29-00
Adénocarcinome du pancréas
Required histologic sub types
Adenocarcinoma
Required disease stage
Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
1
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Gustave Roussy (Villejuif)
Daiichi Sankyo
Phase 2 Prostate cancer #NCT07005154 #2024-517653-27-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic Hormone-sensitive
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Gustave Roussy (Villejuif)
Astellas Pharma Développement mondial, Inc.
Phase 2 Prostate cancer #NCT07005154 #2024-517653-27-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic Castration-resistant
Required number of previous lines of therapy for current stage of disease
None 1
Required previous treatments at advanced or metastatic stage
Hormone therapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Gustave Roussy (Villejuif)
Astellas Pharma Développement mondial, Inc.
Phase 2 Ovarian / Fallopian tubes / Peritoneum cancer #NCT04602377 #2024-515310-40-01
Required histologic types
Other ovarian cancer
Required disease stage
Localized Locally Advanced Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Immunotherapy Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Immunotherapy Chemotherapy
Gustave Roussy (Villejuif)
ARCAGY/ GINECO GROUP
Phase 2 Ovarian / Fallopian tubes / Peritoneum cancer #NCT06690775 #2024-517190-24-00
Required histologic types
Epithelial ovarian cancer Fallopian tube cancer Primary peritoneal cancer (PPC)
Required histologic sub types
Serous high grade carcinoma (HGSOC) Endometrioid carcinoma
Required disease stage
Locally Advanced Metastatic
Required genetic anomalies
Other mutation
Required number of previous lines of therapy for current stage of disease
1 2 3 or more
Required platino resistance
Recurrence within 6 months after platinum-based tr...
Required previous treatments at advanced or metastatic stage
Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Gustave Roussy (Villejuif)
TORL Biotherapeutics, LLC