Cancer clinical trials in the region Normandie

167 currently recruiting clinical trials

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Phase 3 Lung cancer #NCT06430866

NSCLC (Non-Small Cell Lung Cancer) Non-squamous NSCLC Localized Locally Advanced None Surgery Chemotherapy Surgery Chemotherapy

ALK EGFR ROS-1 Immunotherapy Immunotherapy

Centre François Baclesse (Caen )

Amgen

Phase 3 Breast cancer #NCT07060807

[HERTHENA-Breast04] Étude clinique du PATRITUMAB DERUXTECAN pour le traitement du cancer du sein

HER2 Negative HR Positive Locally Advanced Metastatic None 1 Targeted therapy Hormone therapy

BRCA 1/2 Chemotherapy

Centre Henri Becquerel (Rouen )

Merck Sharp & Dohme LLC

Phase 3 Colon cancer Rectal cancer #NCT06293625

[FOxTROT2France] Personnaliser et affiner la chimiothérapie néo-adjuvante dans le cancer du côlon localement avancé mais résécable chez les personnes âgées de 70 ans ou plus

Adenocarcinoma Locally Advanced MSS/pMMR None Systemic Treatment-Naive

MSI/dMMR

Centre Hospitalier Intercommunal Elbeuf - Louviers - Val de Reuil (Saint-Aubin-lès-Elbeuf), Centre Hospitalier Jacques Monod (Flers), Centre Hospitalier Public du Cotentin (Cherbourg-en-Cotentin)

CHU Dijon

Phase 3 Endometrial cancer #NCT06952504 #2024-519331-42-00

[TroFuse-033] Étude comparant le SACITUZUMAB TIRUMOTECANen association avec le PEMBROLIZUMAB et le pembrolizumab seul chez des participantes atteintes d'un cancer de l'endomètre pMMR

Endometrioid adenocarcinoma Serous adenocarcinoma Clear cell carcinoma Dedifferentiated and undifferentiated endometrial ... Locally Advanced Metastatic MSS/pMMR Unknown None Systemic Treatment-Naive

MSI/dMMR Immunotherapy Antibody Drug Conjugates (ADC) Immunotherapy Antibody Drug Conjugates (ADC)

Centre François Baclesse (Caen )

Merck Sharp & Dohme LLC

Phase 3 Lung cancer #NCT06765109 #2024-517553-26-00

[ALKAZAR] Néladalkib pour les patients naïfs de TKI atteints de CBNPC avancé ALK-positif

NSCLC (Non-Small Cell Lung Cancer) Locally Advanced Metastatic ALK None Systemic Treatment-Naive

BRAF EGFR HER2 HRAS KRAS G12C KRAS non G12C MET NTRK-1/2/3 RET ROS-1 Targeted therapy

Centre François Baclesse (Caen )

Nuvalent Inc.

Phase 3 Lymphoma CLL & Richter's syndrome #NCT05254743 #2023-507699-38-00

[BRUIN-CLL-314] Etude sur le PIRTOBRUTINIB par rapport à l'IBRUTINIB chez des participants atteints de leucémie lymphoïde chronique/lymphome à petits lymphocytes - Partie 2

B cell lymphoma CLL (Chronic Lymphocytic Leukemia) Lymphocytic lymphoma None > 60 ml/min 50-60 ml/min 30-50 ml/min None Systemic Treatment-Naive

Centre Henri Becquerel (Rouen )

Loxo Oncology

Phase 3 Lymphoma #NCT06717347 #2024-515566-13-00

[MK-2140-010] Étude visant à évaluer l'association du ZILOVERTAMAB VEDOTINE avec le RITUXIMAB plus CYCLOPHOSPHAMIDE, DOXORUBICINE et PREDNISONE par rapport au RITUXIMAB plus CYCLOPHOSPHAMIDE, DOXORUBICINE, VINCRISTINE et PREDNISONE chez des participants atteints de lymphome diffus à grandes cellules B non traité auparavant

B cell lymphoma Large B cell lymphoma None Treated / Controled None Systemic Treatment-Naive

Centre Henri Becquerel (Rouen )

Merck Sharp & Dohme LLC

Phase 3 Liver and bile duct cancer #NCT05615818 #2023-508100-38-00

[SAFIR-ABC10] Médecine personnalisée pour les patients atteints d'un cancer biliaire avancé

Intrahepatic cholangiocarcinoma Extrahepatic cholangiocarcinoma Locally Advanced Metastatic None Systemic Treatment-Naive

Centre François Baclesse (Caen )

UNICANCER

Phase 3 Lung cancer #NCT06097728 #2023-503231-17-00

[eVOLVE-Meso] MEDI5752 en association avec le CARBOPLATINE et le PEMETREXED dans le mésothéliome pleural non résécable

Mesothelium Locally Advanced Metastatic None

Systemic Treatment-Naive

Centre Henri Becquerel (Rouen )

AstraZeneca

Phase 3 Lymphoma #NCT06191744 #2023-506906-38-00

[EPCORE™FL-2] Étude de l'EPCORITAMAB en association avec le RITUXIMAB et le LENALIDOMIDE chez les participants adultes atteints d'un lymphome folliculaire non traité auparavant

B cell lymphoma Follicular lymphoma None Systemic Treatment-Naive

CHU Caen Normandie (Caen)

Genmab