Clinical trials for Colon cancer

177 currently recruiting clinical trials

Phase 3 Colon cancer Rectal cancer #NCT06197425 #2023-505046-26-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Surgery Chemotherapy
3 recruiting sites
Centre Hospitalier Universitaire Dijon
Phase 3 Colon cancer Rectal cancer #NCT06252649 #2022-502352-31-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic
Required genetic anomalies
KRAS G12C
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Targeted therapy
Excluded previous treatments at advanced or metastatic stage
Targeted therapy
16 recruiting sites
Amgen
Phase 3 Colon cancer Rectal cancer #NCT06107920 #2024-516456-17-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Localized
Required genetic anomalies
MSS/pMMR
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Surgery Chemotherapy Radiotherapy
28 recruiting sites
Hôpital universitaire de Rouen
Phase 3 Colon cancer Rectal cancer #NCT06501482 #2023-504831-42-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
1
Required previous treatments at advanced or metastatic stage
Surgery Chemotherapy
Excluded previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
3 recruiting sites
Assistance Publique - Hôpitaux de Paris
Phase 3 Colon cancer Rectal cancer #NCT04089631 #2018-003691-12
Required disease stage
Localized
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Surgery
Excluded genetic anomalies
MSI/dMMR
5 recruiting sites
Phase 3 Colon cancer #NCT06107920 #2024-516456-17-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Localized
Required genetic anomalies
MSS/pMMR
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Excluded previous treatments at localized stage
Chemotherapy Radiotherapy
3 recruiting sites
CHU Rouen
Phase 3 Colon cancer #NCT05855200 #2023-503265-27-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Localized Locally Advanced
Required genetic anomalies
MSI/dMMR
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded genetic anomalies
MSS/pMMR
9 recruiting sites
GlaxoSmithKline
Phase 3 Colon cancer Rectal cancer #NCT06293625
Required histologic sub types
Adenocarcinoma
Required disease stage
Locally Advanced
Required genetic anomalies
MSS/pMMR
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at localized stage
Systemic Treatment-Naive
Excluded genetic anomalies
MSI/dMMR
57 recruiting sites
CHU Dijon
Phase 3 Colon cancer #NCT06642844
Required histologic sub types
Adenocarcinoma
Required disease stage
Metastatic
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
4 recruiting sites
Centre Hospitalier Universitaire de Tours
Phase 3 Colon cancer Rectal cancer #NCT05253651 #2024-514180-25-00
Required histologic sub types
Adenocarcinoma
Required disease stage
Locally Advanced Metastatic
Required genetic anomalies
HER2
Required number of previous lines of therapy for current stage of disease
None
Required previous treatments at advanced or metastatic stage
Systemic Treatment-Naive
Excluded genetic anomalies
KRAS G12C KRAS non G12C NRAS
18 recruiting sites
Seagen